LABORATORY OF BIOENGINEERING AND REGENERATIVE MEDICINE
The Laboratory of Bioengineering and Regenerative Medicine focuses its efforts on studying age-related dementia (such as Alzheimer’s disease), including molecular mechanisms, epidemiology, genetics, environmental and lifestyle risk factors, search for new diagnostic biomarkers and prophylactics, and treatment strategies. The laboratory conducts investigations of the molecular mechanisms of aging in mesenchymal stem cells to deepen understanding of the aging process of the body. Additionally, the laboratory is developing a method for rejuvenating mesenchymal stem cells isolated from elderly donors, as well as developing and testing new biomaterials for tissue regeneration. The laboratory also conducts research on protein engineering, protein-polymer bioconjugates, and targeted delivery of drugs
MAIN RESEARCH AREAS Infrastructure for the implementation of cell-based therapy in the clinical practice has been established The protocols of primary human neuronal cells extraction and culture have been implemented in research for the first time in KZ The method of stem cells rejuvenation has been developed 3-D in-vivo imaging of laboratory animals has been implemented in research for the first time in KZ A new method for managing of osteoporotic bone fractures has been developed and tested pre-clinically Biologically active wound dressing for wound and burn treatment has been developed and tested pre-clinically Comprehensive research on Alzheimer’s disease has been initiated in KZ for the first time Thermosensitive hydrogel for psoriasis vulgaris treatment has been developed and being tested |
MEMBERS
- Sholpan Askarova, PhDProfessor and Lab Head
- Baurzhan Umbayev, PhDLeading Researcher
- Andrey Tsoy, PhDA/Professor
and Leading Reseacher - B. Kaupbayeva, PhDSenior Researcher
- Yuliya Safarova, PhDSenior Researcher
- Farkhad Olzhayev, MDResearcher
- Aiym Kaiyrlykyzy, MDJunior Researcher
- Aliya KassenovaResearcher
- Aislu YermekovaJunior Researcher
Altyn ZhuraliyevaJunior Researcher
EQUIPMENT
Laboratory has a total area of 340 square meters, clean rooms for cell culture, cold rooms for molecular and biochemical analyses, and general facilities for routine lab methods. The laboratory is provided with different specific and regular lab equipment such as microscopes, centrifuges, water baths, electronic scales, vortexes, shakers, automated pipettes, pH meters, refrigerators and freezers, fume hoods, water-purifying systems, and others.
Laboratory has a total area of 340 square meters, clean rooms for cell culture, cold rooms for molecular and biochemical analyses, and general facilities for routine lab methods. The laboratory is provided with different specific and regular lab equipment such as microscopes, centrifuges, water baths, electronic scales, vortexes, shakers, automated pipettes, pH meters, refrigerators and freezers, fume hoods, water-purifying systems, and others.
Inverted Fully-Motorized and Automated Fluorescent microscope Olympus IX83 and Carl Zeiss Axio Observer Z1
Molecular Imager IVIS Spectrum Spectrum CT (Caliper)
Multiplex protein analyzer MESO QuickPlex SQ 120
Multifunctional Hybrid Plate-Reader Synergy H1
GelDoc Imaging System ChemiDoc MP (Bio-Rad)
Trans-Blot Turbo Transfer System (Bio-Rad)
LyoTRAP
Muse® Cell Analyzer