Risks for tuberculosis in Kazakhstan: implications for prevention

February 3, 2017

 Zhaxybay Zhumadilov, General Director, NLA and Saule Rakimova,  Leading researcher, NLA  published their new research on tuberculosis  in Kazakhstan in the International Journal of Tuberculosis and Lung Disease in cooperation with scientists from Columbia University, New York, USA, Columbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan and National Center for Tuberculosis, Almaty, Kazakhstan. The objective of the study was to examine associations between incarceration history and tobacco, alcohol, and drug consumption, and human immunodeficiency virus (HIV) infection and diabetes mellitus (DM) with TB.

This matched case-control study included 1600 participants who completed a survey on sociodemographics, history of incarceration, tobacco, alcohol and drug use, and HIV and DM diagnosis. Conditional logistic regression analysis was used to examine associations between a TB diagnosis and risk factors.

Participants who had ever smoked tobacco (aOR 1.73, 95%CI 1.23–2.43, P  0.01), ever drank alcohol (aOR 1.41, 95%CI 1.03–1.93, P  0.05), were HIV-positive (aOR 36.37, 95%CI 2.05–646.13, P  0.05) or had DM (aOR 13.96, 95%CI 6.37–30.56, P  0.01) were more likely to have TB.

The association between TB and tobacco use, alcohol use, HIV and DM in Kazakhstan suggests a need for comprehensive intervention and prevention approaches that also address tobacco and alcohol use, DM and HIV.

The International Journal of Tuberculosis and Lung Disease (IF 2.148) publishes articles on all aspects of lung health, including public health-related issues such as training programs, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing  education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide. Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian.