NLA to open joint Laboratory  on Medicine in Shanghai, China.

NLA to open joint Laboratory  on Medicine in Shanghai, China.

June 14, 2017

National Laboratory Astana and  Tongren Hospital in Shanghai, China, which is a major research medical center of the city,  will open a joint international Laboratory  on Medicine,  where different studies of gastrointestinal tract tumors, diseases of neurology, cardiovascular system will be conducted, as well as issues related to aging and diseases associated with aging processes.

According to Professor Zhaxybay Zhumadilov, Director General of National Laboratory Astana, who took direct part in all the negotiations with Chinese colleagues, the starting of a joint Kazakh-Chinese project is a mutually beneficial cooperation for both sides, and it will be very helpful  for scientists  to exchange experience and knowledge more quickly in solving the most important problems of medicine .

2017 NLA newsletter available online

2017 NLA newsletter available online

April 20, 2017

 Newsletter NLA 2017Dear visitor,  read our 2017 NLA newsletter!

NLA scientific article to win the JWOCN Clinical Manuscript Award

NLA scientific article to win the JWOCN Clinical Manuscript Award

April 13, 2017

The scientific paper  A Comprehensive Review on Current Status of Topical Odor Controlling Therapies for Chronic Wounds which has been published in  the Journal of Wound Ostomy & Continence Nursing  has won a prize of this journal JWOCN Clinical Manuscript Award. The authors of this paper are NLA researchers: Talgat Nurgozhin, Director, Center for Life Sciences,  Timur Saliyev, Head of  Laboratory of Translational Medicine and Life Sciences Technologies, NLA, and Alma Akhmetova, Junior researcher, NLA.

The prize will be given at the Conference of Wound, Ostomy and Continence Nurses Society, which will be held  on May, 2017 at  Calvin L. Rampton Salt Palace Convention Center in Salt Lake City, Utah, USA.

In this study our researchers analyzed the process of wound healing, which  is often accompanied by bacterial infection or critical colonization, resulting in protracted inflammation, delayed reepithelization, and production of pungent odors. The malodor produced by these wounds may lower health-related quality of life and produce psychological discomfort and social isolation. Current management focuses on reducing bacterial activity within the wound site and absorbing malodorous gases. For example, charcoal-based materials have been incorporated into dressing for direct adsorption of the responsible gases. In addition, multiple topical agents, including silver, iodine, honey, sugar, and essential oils, have been suggested for incorporation into dressings in an attempt to control the underlying bacterial infection. This review described options for controlling malodor in chronic wounds, the benefits and drawbacks of each topical agent, and their mode of action. Authors also discussed the use of subjective odor evaluation techniques to assess the efficacy of odor-controlling therapies. The perspectives of employing novel biomaterials and technologies for wound odor management were also presented.

To read more visit:

https://www.ncbi.nlm.nih.gov/pubmed/27684356,   

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098468/

Phylogeography of human Y-chromosome haplogroup Q3-L275 from an academic/citizen science collaboration

Phylogeography of human Y-chromosome haplogroup Q3-L275 from an academic/citizen science collaboration

February 13, 2017

Maxsat Zhabagin, researcher, Laboratory For Population Genetics, NLA in cooperation with well-known scientists Oleg Balanovsky, Rebecah Canada, Nadia Al-Zahery  and others published  a new study in BMC Evolutionary Biology  (IF 3,6) on the potential of full Y-chromosome sequencing for reconstructing haplogroup Q3 phylogeography.

Researchers analyzed 47 fully sequenced Y-chromosomes and reconstructed the haplogroup Q3 phylogenetic tree in detail. Haplogroup Q3-L275, derived from the oldest known split within Eurasian/American haplogroup Q, most likely occurred in West or Central Asia in the Upper Paleolithic period. During the Mesolithic and Neolithic epochs, Q3 remained a minor component of the West Asian Y-chromosome pool and gave rise to five branches (Q3a to Q3e), which spread across West, Central and parts of South Asia. Around 3–4 millennia ago (Bronze Age), the Q3a branch underwent a rapid expansion, splitting into seven branches, some of which entered Europe. One of these branches, Q3a1, was acquired by a population ancestral to Ashkenazi Jews and grew within this population during the 1st millennium AD, reaching up to 5% in present day Ashkenazi.

This study dataset was generated by a massive Y-chromosome genotyping effort in the genetic genealogy community, and phylogeographic patterns were revealed by a collaboration of population geneticists and genetic genealogists. This positive experience of collaboration between academic and citizen science provides a model for further joint projects. Merging data and skills of academic and citizen science promises to combine, respectively, quality and quantity, generalization and specialization, and achieve a well-balanced and careful interpretation of the paternal-side history of human populations.

Risks for tuberculosis in Kazakhstan: implications for prevention

Risks for tuberculosis in Kazakhstan: implications for prevention

February 3, 2017

 Zhaxybay Zhumadilov, General Director, NLA and Saule Rakimova,  Leading researcher, NLA  published their new research on tuberculosis  in Kazakhstan in the International Journal of Tuberculosis and Lung Disease in cooperation with scientists from Columbia University, New York, USA, Columbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan and National Center for Tuberculosis, Almaty, Kazakhstan. The objective of the study was to examine associations between incarceration history and tobacco, alcohol, and drug consumption, and human immunodeficiency virus (HIV) infection and diabetes mellitus (DM) with TB.

This matched case-control study included 1600 participants who completed a survey on sociodemographics, history of incarceration, tobacco, alcohol and drug use, and HIV and DM diagnosis. Conditional logistic regression analysis was used to examine associations between a TB diagnosis and risk factors.

Participants who had ever smoked tobacco (aOR 1.73, 95%CI 1.23–2.43, P  0.01), ever drank alcohol (aOR 1.41, 95%CI 1.03–1.93, P  0.05), were HIV-positive (aOR 36.37, 95%CI 2.05–646.13, P  0.05) or had DM (aOR 13.96, 95%CI 6.37–30.56, P  0.01) were more likely to have TB.

The association between TB and tobacco use, alcohol use, HIV and DM in Kazakhstan suggests a need for comprehensive intervention and prevention approaches that also address tobacco and alcohol use, DM and HIV.

The International Journal of Tuberculosis and Lung Disease (IF 2.148) publishes articles on all aspects of lung health, including public health-related issues such as training programs, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing  education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide. Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian.  

Minister to thank NLA General Director

Minister to thank NLA General Director

February 2, 2017

Prof. Zhaxybay Zhumadilov, General Director, National Laboratory Astana was awarded a letter of thanks from Kalmukhanbet Kassymov, Colonel-General, Minister of Internal Affairs of Kazakhstan. Zhaxybay Zhumadilov is a member of the Public Council under the Ministry of Internal Affairs.

The Public Council was established in accordance with the Kazakstani Law "On Public Councils" and the message of the President of the Republic of Kazakhstan “100 concrete steps to implement the five institutional reforms." As it is known, prominent figures of culture, education, science and sport, as well as members of parliament and human rights activists are invited to work for such public councils.  

Minister Kalmukhanbet Kassymov said, members of the Public Council under the Ministry of Internal Affairs conducted a great deal of work, including active participation in  discussions on number of laws  projects during scientific conferences and different level meetings.

NLA Handbook available online

NLA Handbook available online

November 28, 2016

NLA_HB_webDear visitor,

read our new NLA Handbook-2016!

 

Nazarbayev University to win “The most cited scientific organization of Kazakhstan” nomination

Nazarbayev University to win “The most cited scientific organization of Kazakhstan” nomination

November 16, 2016
Nazarbayev University is the best among the most cited scientific organizations of Kazakhstan according to “Thomson Reuters” company.
The award ceremony will be hold soon on 18 November  in the framework of "Science and Innovation - the basis of economic development" forum, which is organized under the auspices of "National Scientific and Technical Information Center" JSC jointly with “Thomson Reuters” company.
Researchers from Nazarbayev University Dr. Almagul Mentbayeva, Adil Ashirbekov, and Marina Kishkentaeva became the winners of «Leader of Science-2016" independent award for high rates of publication activity and citation of information resources according to Web of Science data (Thomson Reuters).
Young scientists have won in the nomination "Articles of Kazakhstan in journals with high impact factor": the leading researcher  of National Laboratory Astana, Nazarbayev University Dr. Almagul Mentbaeva is encouraged for the publication of "Small-moleule-hosting nanocomposite films with multiple bacteria-triggered responses" at «NPG Asia Materials» journal with impact factor 8.77; junior researcher of  School of Education at Nazarbayev University Adil Ashirbekov and NU senior manager Marina Kishkentaeva - for the article "Promoting development of human capital: the typology of international scholarship in the field of higher education programs" in «Educational Researcher» journal with impact factor of 3.05.
It should be reminded that in 2015 the well-known scientists of Nazarbayev University Dr. Zhumabay Bakenov and Dr. Asiya Yermukhambetova also have won «Leader of Science» award according to Thomson Reuters for the joint work with Canadian partners to create the new composite cathodes for the battery.
NLA team to take 1st place in  «BioMAH» conference in  Rome

NLA team to take 1st place in  «BioMAH» conference in  Rome

October 25, 2016

Researchers from the National Laboratory Astana successfully performed during «Biomaterials for Healthcare: Tissue and Genetic Engineering and the Role of Nanotechnology» (BioMAH)  international scientific conference in the heart of Italy, where scientists and biotechnologists from more than twenty-five countries around the world  came together.

This conference covered various issues regarding innovative biomaterials and approaches for tissue regeneration. Its scope was to create a platform for exchanging the latest research results and sharing advanced methods between the scientific community and industries. Participants from various countries attended the conference, among them leading researchers in the biomaterials science field, manufacturers from orthopaedic surgery, neurosurgery, dentistry and pharmaceuticals, engineers, biologists, surgeons, physicians, dentists and other clinical personnel, closely connected with the application of biomaterials.

During the conference NLA’s team from the Laboratory of Bioengineering and Regenerative Medicine presented the results of several research projects in the field of regenerative medicine and tissue bioengineering. The results of the scientific and technological project  such as "Mesenchymal stem cells coated with synthetic bone-targeted polymer as a new approach for managing of osteoporotic bone fracture regeneration" presented by Julia Safarova, NLA junior researcher was highly appreciated by the expert commission of BioMAH- 2016. The project won the first prize in "The best oral young researcher's presentation» nomination.

According to Sholpan  Askarova, head of  Laboratory of  Bioengineering and Regenerative Medicine, NLA given that the osteoporosis is spread  vastly around the world, and due to high level of disability of osteoporosis-related fractures, the scientific group of the laboratory has been developed a method of stimulating the regenerative osteogenesis, including the injection implantation  combined a mesenchymal stem cells coated with synthetic bone-targeted polymer in the zone of osteoporotic bone fracture of the experimental animal model.

This methodology will improve the bone tissue regeneration and can serve as a basis for the development of  the promising cell engineering approaches in the treatment of osteoporosis-related fractures, which will contribute to improving the quality of life and reduce the disability of patients in this category.

Call for applications 2016

Call for applications 2016

October 12, 2016

National Laboratory Astana announces call for applications for seminars and trainings on management of research and GCP. Programs of the seminars will include series of lectures, individual tests for the absorption of the lecture material, group lessons with a tutor, the preparation and presentation of the project research. NLA is an integral part of an integrated academic health system of Nazarbayev University, which includes clinics of National Medical Holding and  University Medical School.  NLA  has already been successfully conducted training seminars and workshops at national and international levels.