Dietary remodeling of intestinal microbiota to reduce the number of cardiovascular events in patients after acute myocardial infarction
IRN AP 09259661
Proven baseline: trimethylamine-N-oxide (TMAO) - a metabolite of the gut microbiota associated with cardiovascular events, and the level of TMOA reflects the risk of atherothrombosis and thromboembolism. Evidence hypothesis: dietary intervention (metabiotic and grape polyphenol concentrate) at the microbiome level to reduce TMAO levels will reduce the number of future cardiovascular events in patients after acute ST-segment elevation myocardial infarction (STEMI).
To prove the possibility of reducing the number of cardiovascular events in patients after acute myocardial infarction during dietary remodeling of the intestinal microbiota with reference to the level of TMAO. Evidence is expected to come from a randomized controlled clinical trial.
Achieving the goal of the project involves the following stages:
First and last names of members of the research group with their identifiers (Scopus Author ID, Researcher ID, ORCID etc.) and links to the relevant profiles:
Zhumadilov Zhaxybay, PhD, prof.
Author ID in Scopus 12546177700 (https://www.scopus.com/authid/detail.uri?authorId=12546177700)
Researcher ID Web of Science D-8117-2012 (https://publons.com/researcher/2735168/zhaxybay-sh-zhumadilov/)
ORCID ID 0000-0003-3855-6429 (https://orcid.org/0000-0003-3855-6429)
Researcher ID in Publons D-8117-2012
Gulyayev Alexander, Doctor of medical science, Prof.
Author ID at Scopus 57188714393 (https://www.scopus.com/authid/detail.uri?authorId=57188714393)
Researcher ID Web of Science AAR-7030-2020 (https://publons.com/researcher/3725824/alexander-gulyayev/)
ORCID ID 0000-0001-5098-4675 (https://orcid.org/0000-0001-5098-4675)
Researcher ID in Publons AAR-7030-2020
Sergazy Shynggys, PhD
Author ID at Scopus 57053283300 (https://www.scopus.com/authid/detail.uri?authorId=57053283300)
Researcher ID Web of Science AAR-6438-2020 (https://publons.com/researcher/3725738/shynggys-sergazy/)
ORCID ID 0000-0002-6030-620X (https://orcid.org/0000-0002-6030-620X)
Researcher ID in Publons AAR-6438-2020